https://www.moleculararchitecture.org/bio daily 0.75 2024-04-13 https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1523294318374-KAI10ZIWRLMTKM9HJ34Q/_Shuguang.JPG About - Laboratory of Molecular Architecture, MIT - Shuguang Zhang https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534463312191-L1O5B0L992XG1C832IWN/MIT_Seal.svg.png About - Laboratory of Molecular Architecture, MIT - Shuguang Zhang https://www.moleculararchitecture.org/fun-readings daily 0.75 2020-11-08 https://www.moleculararchitecture.org/other-papers daily 0.75 2023-08-03 https://www.moleculararchitecture.org/lipidlike-peptides daily 0.75 2018-08-13 https://www.moleculararchitecture.org/news daily 0.75 2020-11-08 https://www.moleculararchitecture.org/reviews daily 0.75 2021-12-04 https://www.moleculararchitecture.org/nature-series daily 0.75 2018-08-12 https://www.moleculararchitecture.org/research daily 0.75 2018-08-28 https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1535242603847-M4Z7U49PIXI9SKOPR2RB/Self-assembling+peptides+0.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang First discovery of self-assembling peptides in yeast. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534557474730-RB2R60JP0FB45KKRVMSP/Biosolar+slide_Page_1.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Biosolar cells. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534554401536-ATFQ2091N1WGLP8KMOSS/Self-assembling+peptides+6.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Design of lipid-like peptides. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534472709974-9DUUCBL1JYVXWSQ5O1FC/Self-assembling+peptides+9.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Lipid-like peptide nanotubes. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534472998612-6PYT7SH36AJP186HJGJ3/3D+cell+biology+5.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Human cells producing Type I and Type III collagen in peptide hydrogel scaffold. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534472719827-8LPZO3SFIF277YJTW3JL/Self-assembling+peptides+10.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Designed surface self-assembling peptides. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534473134981-QCP6EQLJEBLG8MPE7C18/3D+cell+biology+6.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Single peptide to scaffold used for neurons, stem cells, cartilage, bone, and brain tissue repair. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534472315792-FVYFSLD3DXXV5JUKW01A/Self-assembling+peptides+4.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Pathway to a self-assembling single nanofiber. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534472237687-K177TP7V8V0C5SW09W35/Self-assembling+peptides+2.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang From single peptides to peptide nanofibers to a peptide scaffold. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534556481048-8Y6C7ZUSJN369ZM36UHW/3D+cell+biology+1.JPG Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Neural stem cells in self-assembling peptide nanofiber scaffold. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534339416508-WUPM27UXBSN43TAX04W8/4+images+GPCR.JPG Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Water-soluble QTY-variant GPCRs retain form and ligand binding activity in water. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534472413203-4A1G8BM2OFQPNNVBWACT/Self-assembling+peptides+5.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang From peptide scaffold hydrogel to sustained protein release. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534472519640-7D0MZ2G91IXAM51RV8R6/Self-assembling+peptides+7.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang First report of lipid-like peptide nanotubes. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534555139630-O8RJTJLYJUMT9687ER3G/3D+cell+biology+3.JPG Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Cell migration in three dimensions. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534474895632-1EORLPCQGZE68X748IUC/Water+soluble+3.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Four water molecules surround the side chains of glutamine and asparagine, and three water molecules surround the side chains of serine, threonine, and tyrosine. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534472985929-VFRBM11UCWTWD6J41GWJ/3D+cell+biology+4.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Neurons forming synapses in peptide scaffold hydrogel. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534556413077-QYLWQ0WG2NTJDIVPR7KT/3D+cell+biology+2.JPG Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Details of cells embedded in 3-D self-assembling peptide scaffold. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534297392130-H3YVEGOM4ATD0I74XYFY/QTY.png Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Applying the QTY code to design water-soluble variants of GPCRs. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534472273692-DO4AH8KPJB08L6CRL35F/Self-assembling+peptides+3.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang From peptides to hydrogels. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534472694357-7A34TA4QYV9PFHCWRXTS/Self-assembling+peptides+8.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Lipid-like peptide nanotubes. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534475016900-QDKY06HBMLPHUJ99ZHM7/Water+soluble+4.jpg Research - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Structural comparison of designed water-soluble GPCRs and native GPCRs, superimposed, distinguished by color. https://www.moleculararchitecture.org/journal-papers daily 0.75 2018-08-13 https://www.moleculararchitecture.org/conferences daily 0.75 2018-08-25 https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534098042949-9TSUCVRPPMKFU1QPUGRC/2003+Crete+meeting.JPG Conferences - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Third Multidisciplinary Workshop: Self-assembling Peptide and Protein Systems in Biology, Medicine, and Engineering, Crete, Greece, August 2003. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534558473512-36LREN4YURZXNV7B4AZ0/Crete+2005.jpg Conferences - Laboratory of Molecular Architecture, MIT - Shuguang Zhang https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534558561512-0ZHPXI89ZL1UVFCLYK8Q/2005+Crete+meeting.JPG Conferences - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Fourth Multidisciplinary Workshop: Self-assembling Peptide and Protein Systems in Biology, Medicine, and Engineering. Crete, Greece, June 2005. https://www.moleculararchitecture.org/contact daily 0.75 2023-01-14 https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534566491312-K5S0EPYI3F6MOWL5BCWO/mit_seal+1.gif Contact - Laboratory of Molecular Architecture, MIT - Shuguang Zhang https://www.moleculararchitecture.org/pageh daily 1.0 2024-12-07 https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1604873052471-FCJ289B7YFIVOJ5R44X4/Chinese%2Bnewspaper%2Bphoto.jpg Home - Laboratory of Molecular Architecture, MIT - Shuguang Zhang https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/046bac87-71e6-4734-b9d2-20df76ceb01f/MIT-Membrane-Sensors-01-press.jpg Home - Laboratory of Molecular Architecture, MIT - Shuguang Zhang - MIT News (July 21, 2023) New sensor mimics cell membrane functions | MIT News | Massachusetts Institute of Technology An MIT-led team designed a sensor that may be deployed to screen patients for hard-to-diagnose cancers, or metastatic tumors. The device draws inspiration from the membrane that surrounds all cells. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1587072408182-SJY3AQL5MDY27EAHGJN4/Figure+2.png Home - Laboratory of Molecular Architecture, MIT - Shuguang Zhang https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534463172415-YH3B91XESTMCNNJ3Y5R7/MIT_Seal.svg.png Home - Laboratory of Molecular Architecture, MIT - Shuguang Zhang https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1575563603228-6O3GV804JRNTNIUBJM64/CEN+image.jpg Home - Laboratory of Molecular Architecture, MIT - Shuguang Zhang https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1521942204626-30IOQK11PB2TWHLE2NOU/Alpbach+1.jpg Home - Laboratory of Molecular Architecture, MIT - Shuguang Zhang - Shuguang Zhang "If you ask big questions, you get big answers." --Francis Crick Learn more about Shuguang Zhang Curriculum Vitae https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1604872740220-K8NIGS002S0E60BCGTI0/chatterjee_zhang_qing.png Home - Laboratory of Molecular Architecture, MIT - Shuguang Zhang https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/ad48c222-02cc-4b73-aaef-703366de45c2/MIT-Water-Soluble-Proteins-01_0+2024-06-10.jpg Home - Laboratory of Molecular Architecture, MIT - Shuguang Zhang - MIT News (June 10, 2024) Protein study could help researchers develop new antibiotics. Researchers created a water-soluble version of an important bacterial enzyme, which can now be used in drug screens to identify new antibiotics. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1562174242461-YD09ISYGJXHR91SCYJN0/We+are+all+Chinese+Scientists.jpg Home - Laboratory of Molecular Architecture, MIT - Shuguang Zhang We Are All Chinese Scientists https://www.moleculararchitecture.org/photography daily 0.75 2018-08-26 https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1535308493703-7JOXCP4ZPNN4QG01WWH1/QTY+research+team+-+Han+Qiuyi+and+Qing+Rui.png Lab Photography - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Han Qiuyi and Qing Rui https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534565380787-WCNCI46XMJITJEELXEHJ/2003+Crete+meeting+in+Santorini.JPG Lab Photography - Laboratory of Molecular Architecture, MIT - Shuguang Zhang 2003 Zhang Laboratory students at the Crete conference, Santorini excursion. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1535307851730-TDZFWFWUIRZSCPL3MTFN/QTY+research+team+-+Tang+Hongzhi.png Lab Photography - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Tang Hongzhi https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1535308456765-XD9YMYDS7BPFW88BJDWG/QTY+research+team+-+Tao+Fei.png Lab Photography - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Tao Fei https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534565107058-UN7XM02JFDA29R7RIW1M/Lab+group+2008.jpg Lab Photography - Laboratory of Molecular Architecture, MIT - Shuguang Zhang 2008 Zhang Laboratory https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1535308542293-M5S371LC58QRY4HLX6HP/QTY+research+team+-+Michael+Skuhersky.png Lab Photography - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Michael Skuhersky https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534565033169-7MWOMSXFJM9QBAWYGN9J/Lab+group+2007.jpg Lab Photography - Laboratory of Molecular Architecture, MIT - Shuguang Zhang 2007 Zhang Laboratory https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534097741069-4G1ISGW5JAFOMQSZY629/2005+lab+photo.JPG Lab Photography - Laboratory of Molecular Architecture, MIT - Shuguang Zhang 2005 Zhang Laboratory https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534565192661-TQ0RKA0GW2ZBAYC7MN9M/2012-08-22+group.jpg Lab Photography - Laboratory of Molecular Architecture, MIT - Shuguang Zhang 2012 Zhang Laboratory https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1535307808039-YL6MICYIOD7NZLYFDS99/QTY+research+team+-+Karolina+Corin+and+Lotta+Tegler.png Lab Photography - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Karolina Corin and Lotta Tegler https://www.moleculararchitecture.org/the-qty-code daily 0.75 2024-04-13 https://www.moleculararchitecture.org/membrane-proteins daily 0.75 2018-08-13 https://www.moleculararchitecture.org/peptide-scaffolds daily 0.75 2023-01-14 https://www.moleculararchitecture.org/fun-pictures daily 0.75 2018-08-26 https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534561494519-TD16JCWYGH6GE4BE1Q3M/1991+Shuguang%2C+Francis+Crick.jpg Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang With Francis Crick in 1991 in his office in the Salk Institute. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534564779692-F9RTKJFVB567NA1H8F7S/2006+Exener+medal+Austria.jpg Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Receiving the Exener Medal, Vienna, Austria, 2006. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534129590213-G8UA0V3ZWY5KKBWZYYZ2/AIMBE+2011+copy.jpg Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang American Institute of Medical and Biological Engineering, 2011. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534561544936-Q9LGV6XLHMGP8RJVGOH2/2009+SZ+in+Darwin%27s+chair.jpg Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Seated in Charles Darwin's chair to get some ideas about the origins of life. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534562737055-19A7J9UIFIY9D87HGXSG/2013+with+Alex+Rich.jpg Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Alexander Rich, mentor and role model, in Woods Hole, Massachusetts in 2013. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534561952547-ZUI5DMW7IXCIVPJY6RJ0/Crick%2C+Orgel%26Shuguang+copy.JPG Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang With Leslie Orgel and Francis Crick in 1994. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534561537427-OMEGH2Q68UZGY3HH2NI3/Darwin%27s+chair.jpg Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Charles Darwin's chair, according to legend. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534129621425-FYBD9JFU7YY4KLHBC49O/NAI+Conference+Fellows%2C+3-2014+copy.jpg Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang National Academy of Inventors, U.S. Patent Office, 2013. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534563537469-CC47PDIW0J0T8Q9V3D33/image-asset.jpeg Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang In Alexander Rich's lab at MIT. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534561835386-B5MMFQC5V5BYWK4SJDW9/Odile%26Shuguang%2C+2_7_03.jpeg Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang With Odile Crick in their home in 2003. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534564450869-86TI7JYIBYB642IV0Y93/SZ+photos+5-2014_Page_03.jpg Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang With Austrian President Heinz Fischer, Vienna, Austria, 2006. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534563679903-2WMRQP92QS7Z3Y2KE8JI/SZ+photos+5-2014_Page_34.jpg Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang In Shuguang's office at MIT. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534564834255-94L0UXW191GRSZT2JAV6/2010+Austrian+Academy+of+Sciences.jpeg Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Induction into the Austrian Academy of Sciences, 2010. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534562095040-P4HRL8TGBNWHLSJXT5DS/Jean-Marie+Lehn+%26+SZ+copy.JPG Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang With Jean-Marie Lehn in Strasbourg, France, in 2005. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534098760575-WY74CU2N2M3LW1MDZFWH/CIMG0103.JPG Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang With D. Carleton Gajdusek, Aliette and Benoit Mandelbrot, and Andrew Szent-Gyorgyi in 2003. https://images.squarespace-cdn.com/content/v1/5a694c24e45a7c5d46596f1d/1534562341766-9K9G0JFYRHNEDXP6O5XI/Austrian+Academy+of+Sciences+2010.jpeg Fun Pictures - Laboratory of Molecular Architecture, MIT - Shuguang Zhang Austrian Academy of Sciences, 2010.